RSD and Zyprexa

Has anyone heard of a connection with Reflex Sympathetic Dystrophy or nerve damage with the medication Zyprexa

In all the literature online thus far, RSD is not caused by medications. The following is from RSDS.org:

What is CRPS?

Complex Regional Pain Syndrome (CRPS), also known as Reflex Sympathetic Dystrophy, is a chronic neurological syndrome characterized by:

* severe burning pain
* pathological changes in bone and skin
* excessive sweating
* tissue swelling
* extreme sensitivity to touch

[For a complete description of CRPS symptoms, please read the Diagnosis section of the Clinical Practice Guidelines section of this website.]

There are Two Types of CRPS - Type I and Type II

* CRPS Type I (also referred to as RSD) - cases in which the nerve injury cannot be immediately identified
* CRPS Type II (also referred to as Causalgia) - cases in which a distinct "major" nerve injury has occurred
* CRPS is best described in terms of an injury to a nerve or soft tissue (e.g. broken bone) that does not follow the normal healing path
* CRPS development does not appear to depend on the magnitude of the injury. The sympathetic nervous system seems to assume an abnormal function after an injury.
* Since there is no single laboratory test to diagnose CRPS, the physician must assess and document both subjective complaints (medical history) and, if present, objective findings (physical examination).

Criteria for Diagnosing

Complex Regional Pain Syndrome Type I (RSD)

* The presence of an initiating noxious event, or a cause of immobilization
* Continuing pain, allodynia, or hyperalgesia with which the pain is disproportionate to any inciting event
* Evidence at some time of edema, changes in skin blood flow (skin color changes, skin temperature changes more than 1.1°C difference from the homologous body part), or abnormal sudomotor activity in the region of the pain
* This diagnosis is excluded by the existence of conditions that would otherwise account for the degree of pain and dysfunction

Complex Regional Pain Syndrome Type II (Causalgia)

* The presence of continuing pain, allodynia, or hyperalgesia after a nerve injury, not necessarily limited to the distribution of the injured nerve
* Evidence at some time of edema, changes in skin blood flow (skin color changes, skin temperature changes more than 1.1°C difference from the homologous body part), or abnormal sudomotor activity in the region of pain
* This diagnosis is excluded by the existence of conditions that would otherwise account for the degree of pain and dysfunction.

[jenniferchristy]

RSD means Reflex Sympathetic Dystrophy Syndrome.It is also known as Complex Regional Pain Syndrome.The Symptoms Of RSD are
# burning pain
# increased skin sensitivity
# skin temperature changes (warmer or cooler than opposing extremity)
# skin color changes (blotchy, purple, pale, red)
# skin texture changes (shiny, thin, sweaty)

Zyprexa is an atypical antipsychotic medication. Exactly how it works is not known. It is thought to work by changing the actions of certain chemicals in the brain.

# liver disease;
# kidney disease;
# heart disease, high blood pressure, heart rhythm problems;
# high cholesterol or triglycerides;
# a history of heart attack or stroke;
# a history of breast cancer;